Brush Conformation of Polyethylene Glycol Determines the Stealth Effect of Nanocarriers in the Low Protein Adsorption Regime

[Image: see text] For nanocarriers with low protein affinity, we show that the interaction of nanocarriers with cells is mainly affected by the density, the molecular weight, and the conformation of polyethylene glycol (PEG) chains bound to the nanocarrier surface. We achieve a reduction of nonspeci...

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Publicado en:Nano Lett
Main Authors: Li, Mengyi, Jiang, Shuai, Simon, Johanna, Paßlick, David, Frey, Marie-Luise, Wagner, Manfred, Mailänder, Volker, Crespy, Daniel, Landfester, Katharina
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2021
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023711/
https://ncbi.nlm.nih.gov/pubmed/33560851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c03756
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