Brush Conformation of Polyethylene Glycol Determines the Stealth Effect of Nanocarriers in the Low Protein Adsorption Regime

[Image: see text] For nanocarriers with low protein affinity, we show that the interaction of nanocarriers with cells is mainly affected by the density, the molecular weight, and the conformation of polyethylene glycol (PEG) chains bound to the nanocarrier surface. We achieve a reduction of nonspeci...

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Pubblicato in:Nano Lett
Autori principali: Li, Mengyi, Jiang, Shuai, Simon, Johanna, Paßlick, David, Frey, Marie-Luise, Wagner, Manfred, Mailänder, Volker, Crespy, Daniel, Landfester, Katharina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2021
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023711/
https://ncbi.nlm.nih.gov/pubmed/33560851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c03756
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