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Brush Conformation of Polyethylene Glycol Determines the Stealth Effect of Nanocarriers in the Low Protein Adsorption Regime

[Image: see text] For nanocarriers with low protein affinity, we show that the interaction of nanocarriers with cells is mainly affected by the density, the molecular weight, and the conformation of polyethylene glycol (PEG) chains bound to the nanocarrier surface. We achieve a reduction of nonspeci...

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Vydáno v:Nano Lett
Hlavní autoři: Li, Mengyi, Jiang, Shuai, Simon, Johanna, Paßlick, David, Frey, Marie-Luise, Wagner, Manfred, Mailänder, Volker, Crespy, Daniel, Landfester, Katharina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2021
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023711/
https://ncbi.nlm.nih.gov/pubmed/33560851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c03756
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