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A Cu-bis(imidazole) Substrate Intermediate Is the Catalytically Competent Center for Catechol Oxidase Activity of Copper Amyloid-β

[Image: see text] Interaction of copper ions with Aβ peptides alters the redox activity of the metal ion and can be associated with neurodegeneration. Many studies deal with the characterization of the copper binding mode responsible for the reactivity. Oxidation experiments of dopamine and related...

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Detalhes bibliográficos
Publicado no:Inorg Chem
Main Authors: Bacchella, Chiara, Dell’Acqua, Simone, Nicolis, Stefania, Monzani, Enrico, Casella, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023651/
https://ncbi.nlm.nih.gov/pubmed/33405903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.0c02243
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