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Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne “click reaction”

The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences. However, despite many mechanistic studies, direct observation of key components of the catalytic cycl...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Jin, Liqun, Tolentino, Daniel R., Melaimi, Mohand, Bertrand, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640605/
https://ncbi.nlm.nih.gov/pubmed/26601202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500304
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