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Direct Evidence of a Dinuclear Copper Intermediate in Cu(I)-Catalyzed Azide–Alkyne Cycloadditions

The copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) has become a commonly employed method for the synthesis of complex molecular architectures under challenging conditions. Despite the widespread use of copper-catalyzed cycloaddition reactions, the mechanism of these processes has remained di...

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Autori principali: Worrell, B. T., Malik, J. A., Fokin, V. V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651910/
https://ncbi.nlm.nih.gov/pubmed/23558174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1229506
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