Discovery of bone morphogenetic protein 7-derived peptide sequences that attenuate the human osteoarthritic chondrocyte phenotype

Treatment of osteoarthritis (OA) is mainly symptomatic by alleviating pain to postpone total joint replacement. Bone morphogenetic protein 7 (BMP7) is a candidate morphogen for experimental OA treatment that favorably alters the chondrocyte and cartilage phenotype. Intra-articular delivery and susta...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Caron, Marjolein M.J., Ripmeester, Ellen G.J., van den Akker, Guus, Wijnands, Nina K.A. P., Steijns, Jessica, Surtel, Don A.M., Cremers, Andy, Emans, Pieter J., van Rhijn, Lodewijk W., Welting, Tim J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022858/
https://ncbi.nlm.nih.gov/pubmed/33850953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.03.009
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