Impaired chondrocyte U3 snoRNA expression in osteoarthritis impacts the chondrocyte protein translation apparatus

Although pathways controlling ribosome activity have been described to regulate chondrocyte homeostasis in osteoarthritis, ribosome biogenesis in osteoarthritis is unexplored. We hypothesized that U3 snoRNA, a non-coding RNA involved in ribosomal RNA maturation, is critical for chondrocyte protein t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ripmeester, Ellen G. J., Caron, Marjolein M. J., van den Akker, G. G. H., Surtel, Don A. M., Cremers, Andy, Balaskas, Panagiotis, Dyer, Philip, Housmans, Bas A. C., Chabronova, Alzbeta, Smagul, Aibek, Fang, Yongxiang, van Rhijn, Lodewijk W., Peffers, Mandy J., Welting, Tim J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417995/
https://ncbi.nlm.nih.gov/pubmed/32778764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70453-9
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