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Structural insights into redox-active cysteine residues of the Src family kinases

The Src Family Kinases (SFKs) are pivotal regulators of cellular signal transduction and highly sought-after targets in drug discovery. Their actions within cells are controlled by alterations in protein phosphorylation that switch the SFKs from autoinhibited to active states. The SFKs are also well...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Redox Biol
1. Verfasser: Heppner, David E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022254/
https://ncbi.nlm.nih.gov/pubmed/33765616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101934
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