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Structural insights into redox-active cysteine residues of the Src family kinases

The Src Family Kinases (SFKs) are pivotal regulators of cellular signal transduction and highly sought-after targets in drug discovery. Their actions within cells are controlled by alterations in protein phosphorylation that switch the SFKs from autoinhibited to active states. The SFKs are also well...

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Publicado en:Redox Biol
Autor principal: Heppner, David E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022254/
https://ncbi.nlm.nih.gov/pubmed/33765616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101934
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