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Discovery and in-vitro evaluation of potent SARS-CoV-2 entry inhibitors
SARS-CoV-2 infection initiates with the attachment of spike protein to the ACE2 receptor. While vaccines have been developed, no SARS-CoV-2 specific small molecule inhibitors have been approved. Herein, utilizing the crystal structure of the ACE2/Spike receptor binding domain (S-RBD) complex in comp...
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| 出版年: | bioRxiv |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8020965/ https://ncbi.nlm.nih.gov/pubmed/33821265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.02.438204 |
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