Blockade of SARS-CoV-2 infection in vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor

Pathogenic viruses like SARS-CoV-2 and HIV hijack the host molecular machinery to establish infection and survival in infected cells. This has led the scientific community to explore the molecular mechanisms by which SARS-CoV-2 infects host cells, establishes productive infection, and causes life-th...

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Vydáno v:bioRxiv
Hlavní autoři: Acharya, Arpan, Pandey, Kabita, Thurman, Michellie, Challagundala, Kishore B., Vann, Kendra R., Kutateladze, Tatiana G., Morales, Guillermo A, Durden, Donald L., Byrareddy, Siddappa N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941624/
https://ncbi.nlm.nih.gov/pubmed/33688653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.02.433604
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