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Distinct Mucoinflammatory Phenotype and the Immunomodulatory Long Noncoding Transcripts Associated with SARS-CoV-2 Airway Infection

Respiratory epithelial cells are the primary target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We investigated the 3D human airway tissue model to evaluate innate epithelial cell responses to SARS-CoV-2 infection. A SARS-CoV-2 clinical isolate productively infected the 3D-airw...

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Detalhes bibliográficos
Publicado no:medRxiv
Main Authors: Devadoss, Dinesh, Acharya, Arpan, Manevski, Marko, Pandey, Kabita, Borchert, Glen M., Nair, Madhavan, Mirsaeidi, Mehdi, Byrareddy, Siddappa N., Chand, Hitendra S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142670/
https://ncbi.nlm.nih.gov/pubmed/34031668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.13.21257152
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