TAR DNA-Binding Protein 43 Is Associated with Rate of Memory, Functional and Global Cognitive Decline in the Decade Prior to Death

BACKGROUND: Transactive response DNA-binding protein of 43 kDa (TDP-43) is associated with memory impairment and overall cognitive decline. It is unclear how TDP-43 contributes to the rate of clinical decline. OBJECTIVE: To determine whether cross-sectional and longitudinal cognitive and functional...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Buciuc, Marina, Tosakulwong, Nirubol, Machulda, Mary M., Whitwell, Jennifer L., Weigand, Stephen D., Murray, Melissa E., Reichard, R. Ross, Parisi, Joseph E., Dickson, Dennis W., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Josephs, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020877/
https://ncbi.nlm.nih.gov/pubmed/33579840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-201166
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