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Brain atrophy in primary age-related tauopathy is linked to transactive response DNA-binding protein of 43 kDa

INTRODUCTION: Primary age-related tauopathy (PART) is characterized by the presence of neurofibrillary tangles and absent-minimal β-amyloid deposition. Transactive response DNA-binding protein of 43 kDa (TDP-43), a third protein, has recently garnished a lot of attention in Alzheimer’s disease where...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Josephs, Keith A., Murray, Melissa E., Tosakulwong, Nirubol, Weigand, Stephen D., Knopman, David S., Petersen, Ronald C., Jack, Clifford R., Whitwell, Jennifer L., Dickson, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556401/
https://ncbi.nlm.nih.gov/pubmed/31056344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2019.03.003
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