Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43

IMPORTANCE: Transactive response DNA-binding protein 43 (TDP-43) is associated with Alzheimer disease (AD), progressive hippocampal atrophy, and cognitive decline. The apolipoprotein E (APOE) ε4 allele is strongly associated with β-amyloid (Aβ) aggregation and risk of AD, but its association with TD...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Wennberg, Alexandra M., Tosakulwong, Nirubol, Lesnick, Timothy G., Murray, Melissa E., Whitwell, Jennifer L., Liesinger, Amanda M., Petrucelli, Leonard, Boeve, Bradley F., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Dickson, Dennis W., Josephs, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248121/
https://ncbi.nlm.nih.gov/pubmed/30422173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.3139
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