Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

Tauopathies are neurodegenerative disorders with increasing incidence and still without cure. The extensive time required for development and approval of novel therapeutics highlights the need for testing and repurposing known safe molecules. Since doxycycline impacts α-synuclein aggregation and tox...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Medina, Luciana, González-Lizárraga, Florencia, Dominguez-Meijide, Antonio, Ploper, Diego, Parrales, Valeria, Sequeira, Sabrina, Cima-Omori, Maria-Sol, Zweckstetter, Markus, Del Bel, Elaine, Michel, Patrick P., Outeiro, Tiago Fleming, Raisman-Vozari, Rita, Chehín, Rosana, Socias, Sergio B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020845/
https://ncbi.nlm.nih.gov/pubmed/33828477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.635760
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