Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

Tauopathies are neurodegenerative disorders with increasing incidence and still without cure. The extensive time required for development and approval of novel therapeutics highlights the need for testing and repurposing known safe molecules. Since doxycycline impacts α-synuclein aggregation and tox...

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Dettagli Bibliografici
Pubblicato in:Front Aging Neurosci
Autori principali: Medina, Luciana, González-Lizárraga, Florencia, Dominguez-Meijide, Antonio, Ploper, Diego, Parrales, Valeria, Sequeira, Sabrina, Cima-Omori, Maria-Sol, Zweckstetter, Markus, Del Bel, Elaine, Michel, Patrick P., Outeiro, Tiago Fleming, Raisman-Vozari, Rita, Chehín, Rosana, Socias, Sergio B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020845/
https://ncbi.nlm.nih.gov/pubmed/33828477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.635760
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