Structural basis of the activation of a metabotropic GABA receptor

Metabotropic γ-aminobutyric acid receptors (GABA(B)) are involved in the modulation of synaptic responses in the central nervous system and are implicated in various neuropsychological conditions, ranging from addiction to psychosis(1). GABA(B) belongs to G protein-coupled receptor class C, and its...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Shaye, Hamidreza, Ishchenko, Andrii, Lam, Jordy Homing, Han, Gye Won, Xue, Li, Rondard, Philippe, Pin, Jean-Philippe, Katritch, Vsevolod, Gati, Cornelius, Cherezov, Vadim
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020835/
https://ncbi.nlm.nih.gov/pubmed/32555460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2408-4
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