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Structural basis of the activation of a metabotropic GABA receptor

Metabotropic γ-aminobutyric acid receptors (GABA(B)) are involved in the modulation of synaptic responses in the central nervous system and are implicated in various neuropsychological conditions, ranging from addiction to psychosis(1). GABA(B) belongs to G protein-coupled receptor class C, and its...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Shaye, Hamidreza, Ishchenko, Andrii, Lam, Jordy Homing, Han, Gye Won, Xue, Li, Rondard, Philippe, Pin, Jean-Philippe, Katritch, Vsevolod, Gati, Cornelius, Cherezov, Vadim
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020835/
https://ncbi.nlm.nih.gov/pubmed/32555460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2408-4
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