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Physiologically-based pharmacokinetic model for clozapine in Korean patients with schizophrenia
Clozapine has been used as a treatment of schizophrenia. Despite its large interindividual variability, few reports addressed the physiologically-based pharmacokinetic modeling and simulation (PBPK M&S) of clozapine in patients. This study aimed to develop a PBPK M&S of clozapine in Korean p...
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| Publicat a: | Transl Clin Pharmacol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Korean Society for Clinical Pharmacology and Therapeutics
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8020364/ https://ncbi.nlm.nih.gov/pubmed/33854999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2021.29.e3 |
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