Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice

We tested the hypothesis that voluntary wheel running would complement microdystrophin gene therapy to improve muscle function in young mdx mice, a model of Duchenne muscular dystrophy. mdx mice injected with a single dose of AAV9-CK8-microdystrophin or vehicle at age 7 weeks were assigned to three...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther Methods Clin Dev
मुख्य लेखकों: Hamm, Shelby E., Fathalikhani, Daniel D., Bukovec, Katherine E., Addington, Adele K., Zhang, Haiyan, Perry, Justin B., McMillan, Ryan P., Lawlor, Michael W., Prom, Mariah J., Vanden Avond, Mark A., Kumar, Suresh N., Coleman, Kirsten E., Dupont, J.B., Mack, David L., Brown, David A., Morris, Carl A., Gonzalez, J. Patrick, Grange, Robert W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Gene & Cell Therapy 2021
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020351/
https://ncbi.nlm.nih.gov/pubmed/33850950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2021.02.024
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