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AAV-microdystrophin Therapy Improves Cardiac Performance in Aged Female mdx Mice
Dystrophin deficiency leads to lethal dilated Duchenne cardiomyopathy. A promising therapy is to deliver a highly abbreviated microdystrophin gene to the heart using adeno-associated virus (AAV). Microdystrophin has been shown to mitigate dystrophin-deficient skeletal muscle disease. However, it is...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188746/ https://ncbi.nlm.nih.gov/pubmed/21811246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.154 |
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