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SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice
BACKGROUND: Cardiomyocyte calcium overloading has been implicated in the pathogenesis of Duchenne muscular dystrophy (DMD) heart disease. The cardiac isoform of sarcoplasmic reticulum calcium ATPase (SERCA2a) plays a major role in removing cytosolic calcium during heart muscle relaxation. Here, we t...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162513/ https://ncbi.nlm.nih.gov/pubmed/21834967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-132 |
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