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Increased IL-6 and Potential IL-6 Trans-signaling in the Airways after an Allergen Challenge

BACKGROUND: In asthma, IL-6 is a potential cause of enhanced inflammation, tissue damage and airway dysfunction. IL-6 signaling is regulated by its receptor, which is composed of two proteins, IL-6R and GP130. In addition to their membrane form, these two proteins may be found as extracellular solub...

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Bibliografski detalji
Izdano u:Clin Exp Allergy
Glavni autori: Esnault, Stephane, Khosravi, Mehdi, Becky Kelly, Elizabeth A., Liu, Lin-Ying, Bochkov, Yury A., Tattersall, Matthew C., Jarjour, Nizar N.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020336/
https://ncbi.nlm.nih.gov/pubmed/33471392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13832
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