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Human Airway Epithelial Cells Express a Functional IL-5 Receptor

We found that HBEC expressed the IL-5 receptor, which triggered intracellular signaling and changed gene expression. This data indicate that in addition to targeting eosinophils, IL-5 and anti-IL-5 biologics may have a direct role on AEC.

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Detalhes bibliográficos
Publicado no:Allergy
Main Authors: Barretto, Karina T., Brockman-Schneider, Rebecca A., Kuipers, Ine, Basnet, Sarmila, Bochkov, Yury A., Altman, Matthew C., Jarjour, Nizar N., Gern, James E., Esnault, Stephane
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387204/
https://ncbi.nlm.nih.gov/pubmed/32246831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14297
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