CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections

CDHR3 (cadherin-related family member 3) is a transmembrane protein that is highly expressed in airway epithelia and the only known receptor for rhinovirus C (RV-C). A CDHR3 SNP (rs6967330) with G to A base change has been linked to severe exacerbations of asthma and increased susceptibility to RV-C...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Basnet, Sarmila, Bochkov, Yury A., Brockman-Schneider, Rebecca A., Kuipers, Ine, Aesif, Scott W., Jackson, Daniel J., Lemanske, Robert F., Ober, Carol, Palmenberg, Ann C., Gern, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775945/
https://ncbi.nlm.nih.gov/pubmed/30916989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0220OC
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