Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) can render monoclonal antibodies ineffective. Here, we completely map all of th...

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Foilsithe in:Cell Rep Med
Main Authors: Starr, Tyler N., Greaney, Allison J., Dingens, Adam S., Bloom, Jesse D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2021
Ábhair:
Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020059/
https://ncbi.nlm.nih.gov/pubmed/33842902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100255
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