The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies are a key class of therapeutics that may bridge widespread vaccination campaigns and offer a treatment solution in popula...

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Vydáno v:Sci Transl Med
Hlavní autoři: Jones, Bryan E., Brown-Augsburger, Patricia L., Corbett, Kizzmekia S., Westendorf, Kathryn, Davies, Julian, Cujec, Thomas P., Wiethoff, Christopher M., Blackbourne, Jamie L., Heinz, Beverly A., Foster, Denisa, Higgs, Richard E., Balasubramaniam, Deepa, Wang, Lingshu, Zhang, Yi, Yang, Eun Sung, Bidshahri, Roza, Kraft, Lucas, Hwang, Yuri, Žentelis, Stefanie, Jepson, Kevin R., Goya, Rodrigo, Smith, Maia A., Collins, David W., Hinshaw, Samuel J., Tycho, Sean A., Pellacani, Davide, Xiang, Ping, Muthuraman, Krithika, Sobhanifar, Solmaz, Piper, Marissa H., Triana, Franz J., Hendle, Jorg, Pustilnik, Anna, Adams, Andrew C., Berens, Shawn J., Baric, Ralph S., Martinez, David R., Cross, Robert W., Geisbert, Thomas W., Borisevich, Viktoriya, Abiona, Olubukola, Belli, Hayley M., de Vries, Maren, Mohamed, Adil, Dittmann, Meike, Samanovic, Marie I., Mulligan, Mark J., Goldsmith, Jory A., Hsieh, Ching-Lin, Johnson, Nicole V., Wrapp, Daniel, McLellan, Jason S., Barnhart, Bryan C., Graham, Barney S., Mascola, John R., Hansen, Carl L., Falconer, Ester
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284311/
https://ncbi.nlm.nih.gov/pubmed/33820835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abf1906
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