From Good to Bad: The Opposing Effects of PTHrP on Tumor Growth, Dormancy, and Metastasis Throughout Cancer Progression

Parathyroid hormone related protein (PTHrP) is a multifaceted protein with several biologically active domains that regulate its many roles in normal physiology and human disease. PTHrP causes humoral hypercalcemia of malignancy (HHM) through its endocrine actions and tumor-induced bone destruction...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Edwards, Courtney M., Johnson, Rachelle W.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019909/
https://ncbi.nlm.nih.gov/pubmed/33828987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.644303
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