PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

Parathyroid hormone–related protein (PTHrP) is a secreted factor expressed in almost all normal fetal and adult tissues. It is involved in a wide range of developmental and physiological processes, including serum calcium regulation. PTHrP is also associated with the progression of skeletal metastas...

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Autori principali: Li, Jiarong, Karaplis, Andrew C., Huang, Dao C., Siegel, Peter M., Camirand, Anne, Yang, Xian Fang, Muller, William J., Kremer, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225988/
https://ncbi.nlm.nih.gov/pubmed/22056386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46134
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