The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development

Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients, but with an accelerated timeframe. This rapid effect on weight-bearing bones is also observed in astronauts who can lose up to 2% of their bone mass per month spent in Space....

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Udgivet i:PLoS One
Main Authors: Camirand, Anne, Goltzman, David, Gupta, Ajay, Kaouass, Mohammadi, Panda, Dibyendu, Karaplis, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963112/
https://ncbi.nlm.nih.gov/pubmed/27463808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160034
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