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The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development

Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients, but with an accelerated timeframe. This rapid effect on weight-bearing bones is also observed in astronauts who can lose up to 2% of their bone mass per month spent in Space....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Camirand, Anne, Goltzman, David, Gupta, Ajay, Kaouass, Mohammadi, Panda, Dibyendu, Karaplis, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963112/
https://ncbi.nlm.nih.gov/pubmed/27463808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160034
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