Parathyroid hormone-related peptide (PTHrP) regulates fetal–placental calcium transport through a receptor distinct from the PTH/PTHrP receptor

To determine the role of PTHrP in fetal calcium metabolism, blood calcium was measured in mice homozygous (HOM) for deletion of the PTHrP gene. On day 18.5 of gestation, ionized calcium and the maternal–fetal calcium gradient were significantly reduced in HOM PTHrP-ablated fetuses compared with that...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kovacs, Christopher S., Lanske, Beate, Hunzelman, Joy L., Guo, Jun, Karaplis, Andrew C., Kronenberg, Henry M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26386/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15233
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