Parathyroid hormone-related peptide (PTHrP) regulates fetal–placental calcium transport through a receptor distinct from the PTH/PTHrP receptor

To determine the role of PTHrP in fetal calcium metabolism, blood calcium was measured in mice homozygous (HOM) for deletion of the PTHrP gene. On day 18.5 of gestation, ionized calcium and the maternal–fetal calcium gradient were significantly reduced in HOM PTHrP-ablated fetuses compared with that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kovacs, Christopher S., Lanske, Beate, Hunzelman, Joy L., Guo, Jun, Karaplis, Andrew C., Kronenberg, Henry M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences of the USA 1996
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC26386/
https://ncbi.nlm.nih.gov/pubmed/8986793
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