RIPK3 Induces Cardiomyocyte Necroptosis via Inhibition of AMPK-Parkin-Mitophagy in Cardiac Remodelling after Myocardial Infarction

Receptor-interacting protein 3- (RIPK3-) modulated necroptosis plays a critical role in cardiac remodelling after myocardial infarction (MI). However, the precise regulatory mechanism is not fully elucidated yet. In the present study, we showed that RIPK3 expression was upregulated in myocardial tis...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhu, Pingjun, Wan, Kun, Yin, Ming, Hu, Peng, Que, Yifan, Zhou, Xin, Zhang, Lei, Li, Tianzhi, Du, Yingzhen, Xu, Guogang, Fang, Xiangqun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019651/
https://ncbi.nlm.nih.gov/pubmed/33854696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6635955
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