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5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19

The 5-HT1A receptor is a G protein coupled receptor (GPCR) that activates G proteins of the Gαi/o family. 5-HT1A receptors expressed in the raphe, hippocampus and prefrontal cortex are implicated in the control of mood and are targets for anti-depressant drugs. Regulators of G protein signaling (RGS...

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Pubblicato in:Cell Signal
Autori principali: Wang, Qin, Terauchi, Akiko, Yee, Christopher H., Umemori, Hisashi, Traynor, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019269/
https://ncbi.nlm.nih.gov/pubmed/24793302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.04.017
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