β-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT(4) receptor signalling

G protein-coupled receptors (GPCRs) have been found to trigger G protein-independent signalling. However, the regulation of G protein-independent pathways, especially their desensitization, is poorly characterized. Here, we show that the G protein-independent 5-HT(4) receptor (5-HT(4)R)-operated Src...

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Main Authors: Barthet, Gaël, Carrat, Gaëlle, Cassier, Elizabeth, Barker, Breann, Gaven, Florence, Pillot, Marion, Framery, Bérénice, Pellissier, Lucie P, Augier, Julie, Kang, Dong Soo, Claeysen, Sylvie, Reiter, Eric, Banères, Jean-Louis, Benovic, Jeffrey L, Marin, Philippe, Bockaert, Joël, Dumuis, Aline
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750015/
https://ncbi.nlm.nih.gov/pubmed/19661922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.215
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