BRAF V600E mutant oligodendroglioma‐like tumors with chromosomal instability in adolescents and young adults

We performed genome‐wide methylation analysis on 136 pediatric low‐grade gliomas, identifying a unique cluster consisting of three tumors with oligodendroglioma‐like histology, BRAF p.V600E mutations and recurrent whole chromosome gains of 7 and loss of 10. Morphologically, all showed similar featur...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Fukuoka, Kohei, Mamatjan, Yasin, Ryall, Scott, Komosa, Martin, Bennett, Julie, Zapotocky, Michal, Keith, Julia, Myrehaug, Sten, Hazrati, Lili‐Naz, Aldape, Kenneth, Laperriere, Norm, Bouffet, Eric, Tabori, Uri, Hawkins, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018140/
https://ncbi.nlm.nih.gov/pubmed/31630459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12799
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