LGG-01. BRAF V600E MUTANT OLIGODENDROGLIOMA-LIKE TUMORS WITH CHROMOSOMAL INSTABILITY IN ADOLESCENT AND YOUNG ADULT

We performed genome-wide methylation analysis on 136 pediatric low grade gliomas, identifying a unique cluster consisting of BRAF V600E mutant tumors with chromosomal instability, including gain of Chromosome 7 and loss of Chromosome 10. The tumors were all located in the temporal lobe. Patients pre...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Fukuoka, Kohei, Yashin, Mamatjan, Ryall, Scott, Komosa, Martin, Benett, Julie, Zapotocky, Michal, Keith, Julia, Myrehaug, Sten, Hazrati, Lili-Naz, Aldape, Kenneth, Laperriere, Norm, Bouffet, Eric, Tabori, Uri, Hawkins, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Low Grade Glioma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477275/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.144
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