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A machine learning-based framework for modeling transcription elongation

RNA polymerase II (Pol II) generally pauses at certain positions along gene bodies, thereby interrupting the transcription elongation process, which is often coupled with various important biological functions, such as precursor mRNA splicing and gene expression regulation. Characterizing the transc...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Feng, Peiyuan, Xiao, An, Fang, Meng, Wan, Fangping, Li, Shuya, Lang, Peng, Zhao, Dan, Zeng, Jianyang
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017690/
https://ncbi.nlm.nih.gov/pubmed/33526657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007450118
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