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A machine learning-based framework for modeling transcription elongation

RNA polymerase II (Pol II) generally pauses at certain positions along gene bodies, thereby interrupting the transcription elongation process, which is often coupled with various important biological functions, such as precursor mRNA splicing and gene expression regulation. Characterizing the transc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Feng, Peiyuan, Xiao, An, Fang, Meng, Wan, Fangping, Li, Shuya, Lang, Peng, Zhao, Dan, Zeng, Jianyang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017690/
https://ncbi.nlm.nih.gov/pubmed/33526657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007450118
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