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EXP2SL: A Machine Learning Framework for Cell-Line-Specific Synthetic Lethality Prediction

Synthetic lethality (SL), an important type of genetic interaction, can provide useful insight into the target identification process for the development of anticancer therapeutics. Although several well-established SL gene pairs have been verified to be conserved in humans, most SL interactions rem...

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Podrobná bibliografie
Vydáno v:Front Pharmacol
Hlavní autoři: Wan, Fangping, Li, Shuya, Tian, Tingzhong, Lei, Yipin, Zhao, Dan, Zeng, Jianyang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058988/
https://ncbi.nlm.nih.gov/pubmed/32184722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00112
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