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EXP2SL: A Machine Learning Framework for Cell-Line-Specific Synthetic Lethality Prediction

Synthetic lethality (SL), an important type of genetic interaction, can provide useful insight into the target identification process for the development of anticancer therapeutics. Although several well-established SL gene pairs have been verified to be conserved in humans, most SL interactions rem...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wan, Fangping, Li, Shuya, Tian, Tingzhong, Lei, Yipin, Zhao, Dan, Zeng, Jianyang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058988/
https://ncbi.nlm.nih.gov/pubmed/32184722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00112
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