miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a

Compromised cardiac function is a hallmark for heart failure, mostly appearing as decreased contractile capacity due to dysregulated calcium handling. Unfortunately, the underlying mechanism causing impaired calcium handling is still not fully understood. Previously the miR-132/212 family was identi...

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Detalles Bibliográficos
Publicado en:Front Cardiovasc Med
Autores principales: Lei, Zhiyong, Wahlquist, Christine, el Azzouzi, Hamid, Deddens, Janine C., Kuster, Diederik, van Mil, Alain, Rojas-Munoz, Agustin, Huibers, Manon M., Mercola, Mark, de Weger, Roel, Van der Velden, Jolanda, Xiao, Junjie, Doevendans, Pieter A., Sluijter, Joost P. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017124/
https://ncbi.nlm.nih.gov/pubmed/33816571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.592362
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