miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a

Compromised cardiac function is a hallmark for heart failure, mostly appearing as decreased contractile capacity due to dysregulated calcium handling. Unfortunately, the underlying mechanism causing impaired calcium handling is still not fully understood. Previously the miR-132/212 family was identi...

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Bibliografski detalji
Izdano u:Front Cardiovasc Med
Glavni autori: Lei, Zhiyong, Wahlquist, Christine, el Azzouzi, Hamid, Deddens, Janine C., Kuster, Diederik, van Mil, Alain, Rojas-Munoz, Agustin, Huibers, Manon M., Mercola, Mark, de Weger, Roel, Van der Velden, Jolanda, Xiao, Junjie, Doevendans, Pieter A., Sluijter, Joost P. G.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Cardiovascular Medicine
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017124/
https://ncbi.nlm.nih.gov/pubmed/33816571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.592362
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