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Hemoglobin induces oxidative stress and mitochondrial dysfunction in oligodendrocyte progenitor cells

Oligodendrocyte progenitor cells (OPCs) in the infant brain give rise to mature oligodendrocytes that myelinate CNS axons. OPCs are particularly vulnerable to oxidative stress that occurs in many forms of brain injury. One common cause of infant brain injury is neonatal intraventricular hemorrhage (...

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Vydáno v:Transl Res
Hlavní autoři: Pandya, Chirayu D., Vekaria, Hemendra, Joseph, Binoy, Slone, Stacey A., Gensel, John C., Sullivan, Patrick G., Miller, Brandon A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016702/
https://ncbi.nlm.nih.gov/pubmed/33460824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2021.01.005
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