Hemoglobin induces oxidative stress and mitochondrial dysfunction in oligodendrocyte progenitor cells

Oligodendrocyte progenitor cells (OPCs) in the infant brain give rise to mature oligodendrocytes that myelinate CNS axons. OPCs are particularly vulnerable to oxidative stress that occurs in many forms of brain injury. One common cause of infant brain injury is neonatal intraventricular hemorrhage (...

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Détails bibliographiques
Publié dans:Transl Res
Auteurs principaux: Pandya, Chirayu D., Vekaria, Hemendra, Joseph, Binoy, Slone, Stacey A., Gensel, John C., Sullivan, Patrick G., Miller, Brandon A.
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016702/
https://ncbi.nlm.nih.gov/pubmed/33460824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2021.01.005
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