Hemoglobin induces oxidative stress and mitochondrial dysfunction in oligodendrocyte progenitor cells

Oligodendrocyte progenitor cells (OPCs) in the infant brain give rise to mature oligodendrocytes that myelinate CNS axons. OPCs are particularly vulnerable to oxidative stress that occurs in many forms of brain injury. One common cause of infant brain injury is neonatal intraventricular hemorrhage (...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Pandya, Chirayu D., Vekaria, Hemendra, Joseph, Binoy, Slone, Stacey A., Gensel, John C., Sullivan, Patrick G., Miller, Brandon A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016702/
https://ncbi.nlm.nih.gov/pubmed/33460824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2021.01.005
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