Vitronectin‐activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells

OBJECTIVES: Vitronectin (VTN) has been widely used for the maintenance and expansion of human pluripotent stem cells (hPSCs) as feeder‐free conditions. However, the effect of VTN on hPSC differentiation remains unclear. Here, we investigated the role of VTN in early haematopoietic development of hPS...

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Veröffentlicht in:Cell Prolif
Hauptverfasser: Shen, Jun, Zhu, Yaoyao, Zhang, Shuo, Lyu, Shuzhen, Lyu, Cuicui, Feng, Zicen, Hoyle, Dixie L., Wang, Zack Z., Cheng, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016644/
https://ncbi.nlm.nih.gov/pubmed/33656760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13012
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