Vitronectin‐activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells

OBJECTIVES: Vitronectin (VTN) has been widely used for the maintenance and expansion of human pluripotent stem cells (hPSCs) as feeder‐free conditions. However, the effect of VTN on hPSC differentiation remains unclear. Here, we investigated the role of VTN in early haematopoietic development of hPS...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Shen, Jun, Zhu, Yaoyao, Zhang, Shuo, Lyu, Shuzhen, Lyu, Cuicui, Feng, Zicen, Hoyle, Dixie L., Wang, Zack Z., Cheng, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016644/
https://ncbi.nlm.nih.gov/pubmed/33656760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13012
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