Baricitinib restrains the immune dysregulation in patients with severe COVID-19

BACKGROUND: Patients with coronavirus disease 2019 (COVID-19) develop pneumonia generally associated with lymphopenia and a severe inflammatory response due to uncontrolled cytokine release. These mediators are transcriptionally regulated by the JAK/STAT signaling pathways, which can be disabled by...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Bronte, Vincenzo, Ugel, Stefano, Tinazzi, Elisa, Vella, Antonio, De Sanctis, Francesco, Canè, Stefania, Batani, Veronica, Trovato, Rosalinda, Fiore, Alessandra, Petrova, Varvara, Hofer, Francesca, Barouni, Roza Maria, Musiu, Chiara, Caligola, Simone, Pinton, Laura, Torroni, Lorena, Polati, Enrico, Donadello, Katia, Friso, Simonetta, Pizzolo, Francesca, Iezzi, Manuela, Facciotti, Federica, Pelicci, Pier Giuseppe, Righetti, Daniela, Bazzoni, Paolo, Rampudda, Mariaelisa, Comel, Andrea, Mosaner, Walter, Lunardi, Claudio, Olivieri, Oliviero
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Clinical Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016181/
https://ncbi.nlm.nih.gov/pubmed/32809969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI141772
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