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TCR(+)/BCR(+) dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes

Ahmed and colleagues recently described a novel hybrid lymphocyte expressing both a B and T cell receptor, termed double expresser (DE) cells. DE cells in blood of T1D subjects were present at increased numbers and enriched for a public B cell clonotype. Here, we attempted to reproduce these finding...

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Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Japp, Alberto Sada, Meng, Wenzhao, Rosenfeld, Aaron M., Perry, Daniel J., Thirawatananond, Puchong, Bacher, Rhonda L., Liu, Chengyang, Gardner, Jay S., Atkinson, Mark A., Kaestner, Klaus H., Brusko, Todd M., Naji, Ali, Luning Prak, Eline T., Betts, Michael R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016147/
https://ncbi.nlm.nih.gov/pubmed/33545036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.11.035
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